Thermal Extraction Devices

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    Thermal engineering & extraction device archive

    Cannabidivarin (CBDV)

    Identity

    Property Value
    Preferred name Cannabidivarin (CBDV)
    IUPAC name 2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol
    CAS number 24274-48-4
    PubChem CID 11601669
    Molecular formula C19H26O2
    Molecular mass 286.41 g/mol (exact 286.1933 Da)
    Compound class Phytocannabinoid; propyl homologue of CBD (C19 series vs. C21)
    Stereochemistry Two stereocenters; natural material is (−)-CBDV with (1R,6R) geometry; synthetic racemates exist [^1]
    Major synonyms Cannabidivarin, CBDV; its acid precursor is CBDVA (no separate archive page in this wave)

    Identity notes

    • CBDV shares the molecular formula C19H26O2 with CBCV (cannabichromevarin); chromatographic separation is required [^1].
    • InChIKey for CBDV was not confirmed in the available source notes and is not asserted here; confirm before machine use [^1].

    Physical properties

    Property Value Conditions / Notes
    Boiling point No compound-specific atmospheric boiling point was located for CBDV. Do not substitute CBD’s extrapolation or a device temperature; the atmospheric value remains unresolved [^2][^3]
    Vapor pressure Not measured; no compound-specific vapor-pressure curve was located. CBD’s measured curve is evidence for CBD only; relative CBDV volatility remains unresolved [^2]
    Melting point Not reported in authoritative sources Expected similar to or slightly below CBD (≈66 °C)
    logP (octanol-water) Predicted ≈5.7–6.0 Slightly lower than CBD
    Water solubility Practically insoluble (<1 µg/mL estimated) Soluble in ethanol, methanol, DMSO, lipids
    Thermal decomposition Not independently characterized for CBDV; no compound-specific decomposition threshold is assigned. CBD degradation data are an analogy, not a CBDV sample-temperature result [^4]
    Oxidation / light sensitivity High; polyphenolic structure vulnerable to air and UV (by analogy to CBD) [^4]
    Known degradation products [^4]

    Boiling point is not a device setpoint. The commonly cited “CBDV boiling point ≈160–180 °C” is not supported as a CBDV thermodynamic property. It must not be used as a device setpoint or as the sample temperature [^3].

    Thermal-extraction context

    As with CBD, thermal release from a plant matrix may involve vapor-pressure-driven evaporation after any acid-form material has decarboxylated, but CBDV-specific release and degradation data are unresolved. The thermodynamic boiling point of the pure compound is not a device setpoint or a sample temperature; the device setpoint and actual sample temperature must be measured separately.

    Cannabis occurrence

    CBDV is a minor cannabinoid in most measured chemotypes and is reported in higher relative amounts in some landrace and propyl-series cultivars; values remain batch- and report-attached. Consult Lab Results for batch-level measurements.

    Reported biological activity

    Human evidence

    No controlled human study of inhaled isolated CBDV was identified in this archive’s literature review (as of 2026-08-08).

    Preclinical animal and in vitro evidence

    Early preclinical work investigated CBDV for anticonvulsant activity in animal seizure models 1; no human clinical effect at consumer-relevant doses is established.

    Industry claims

    Minor-cannabinoid marketing claims for CBDV remain unsupported by controlled human evidence.

    Degradation products

    • Predicted by analogy to CBD: CBEV-type products, hydroxyquinones (HU-331 analog), CBNV

    Sources

    1. Hill AJ, Mercier MS, Hill TD, Glyn SE, Jones NA, Yamasaki Y, et al. Cannabidivarin is anticonvulsant in mouse and rat in vitro and in seizure models. Br J Pharmacol. 2012;167(8):1629–1642. doi:10.1111/j.1476-5381.2012.02207.x. PMID 22970845. (Animal/in vitro study.) ↩

    Derived navigation generated from structured relationships. Links are labeled by edge class and evidence trace; derived links are navigation, not primary assertions.

    Laboratory reports measuring this compound (1)

    Products with measurements (1)

    Related (2)