Δ9-Tetrahydrocannabivarin (THCV)
Identity
| Property | Value |
|---|---|
| Preferred name | Δ9-Tetrahydrocannabivarin (THCV) |
| IUPAC name | (6aR,10aR)-6,6,9-trimethyl-3-propyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol |
| CAS number | 31262-37-0 |
| PubChem CID | 93147 |
| InChIKey | RQJXOVYKMPKZOV-ZXZARUISSA-N [^1] |
| Molecular formula | C19H26O2 |
| Molecular mass | 286.41 g/mol (exact 286.1933 Da) |
| Compound class | Phytocannabinoid; propyl homologue of Δ9-THC (C19 series vs. C21) |
| Stereochemistry | Natural material is (6aR,10aR). Δ8-THCV (CAS 31262-38-1) is a distinct positional isomer [^1] |
| Major synonyms | THCV, Δ9-THCV; its acid precursor is THCVA (no separate archive page in this wave) |
Identity notes
- Δ9-THCV (31262-37-0) and Δ8-THCV (31262-38-1) have distinct CAS numbers and retention times; GC without chiral or isomer-resolving separation may merge them [^1].
- THCV (C19) vs. THC (C21): the propyl vs. pentyl side chain must not be collapsed in reporting [^1].
Physical properties
| Property | Value | Conditions / Notes |
|---|---|---|
| Boiling point | No compound-specific atmospheric boiling point was located for THCV. Predicted values and the “220 °C” blog claim are not verified THCV measurements; the atmospheric value remains unresolved [^5] | |
| Boiling point (reduced pressure) | No compound-specific reduced-pressure boiling datum was independently verified; the value remains unresolved | THC vacuum-distillation data are not a THCV measurement [^2][^5] |
| Vapor pressure | Not directly measured; no compound-specific vapor-pressure curve was located. Δ9-THC values are an analogy only and must not be presented as THCV data | Relative THCV volatility remains unresolved [^2] |
| Melting point | Not reported in authoritative sources | Likely amorphous/semi-solid at room temperature |
| logP (octanol-water) | ≈5.5–6.0 (estimated) | Propyl chain lowers logP vs. THC |
| Water solubility | Practically insoluble | Soluble in ethanol, methanol, hydrocarbons, CO₂ |
| Thermal decomposition | No direct THCV thermal-decomposition curve was located; THC/THCVA study conditions are not a THCV sample-temperature threshold, so stability at device-relevant sample temperatures remains unresolved [^3][^4] | |
| Oxidation / light sensitivity | THCV-specific oxidation and light-stability rates are not directly characterized; no stability threshold is assigned [^4] | |
| Known degradation products | Secondary products are not fully characterized; propyl-CBN-type, quinone, and polymeric assignments remain unresolved analogies [^4] |
Boiling point is not a device setpoint. “THCV boils at 220 °C” is not a verified THCV thermodynamic measurement; it may conflate a vaporizer chamber setting with the sample temperature [^5]. No compound-specific atmospheric boiling point was located.
Thermal-extraction context
As with THC, thermal release may involve decarboxylation of THCVA to THCV followed by vapor-pressure-driven evaporation from the matrix, but THCV-specific device/sample-temperature behavior is unresolved. The thermodynamic boiling point of the pure compound is not a device setpoint or a sample temperature; actual matrix release must be measured under stated conditions [^2][^3].
Cannabis occurrence
THCV is a minor cannabinoid in most measured chemotypes, elevated in certain African and Asian landrace lines and in cultivars bred for high THCV; values remain batch- and report-attached. Consult Lab Results for batch-level measurements.
Reported biological activity
Human evidence
No controlled human study of inhaled isolated THCV was identified in this archive’s literature review (as of 2026-08-08).
Preclinical animal and in vitro evidence
Preclinical studies report THCV as a CB1 and CB2 receptor antagonist 1; appetite-suppressant claims derive from animal work and small mechanistic studies, not established human clinical effects.
Industry claims
“THCV suppresses appetite” and “THCV is the diet weed” are marketing framings exceeding the current evidence; no controlled human study establishes these effects.
Degradation products
- Oxidation: unresolved; propyl-CBN-type analogs, quinones, and polymeric material require compound-specific confirmation
Sources
Related pages
- Cannabinoids Index
- THCA Record (pentyl homologue)
-
Thomas A, Stevenson LA, Wease KN, Price MR, Baillie G, Ross RA, Pertwee RG. Evidence that the plant cannabinoid Δ9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist. Br J Pharmacol. 2005;146(6):917–926. doi:10.1038/sj.bjp.0706414. PMID 16205722. (In vitro receptor pharmacology.) ↩
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Laboratory reports measuring this compound (1)
- Verified COA: Dragonberry 750ml (10mg) — Batch 250410-37-002 (InfiniteCAL) verified via 1 record(s)
Products with measurements (1)
- Dragonberry 750ml (10mg) — Powered By Plants verified via 1 record(s)