α-Bisabolol
Identity
| Property | Value |
|---|---|
| Preferred name | α-Bisabolol (Levomenol) |
| IUPAC name | 1-methyl-4-(6-methylhept-5-en-2-yl)cyclohex-3-ene-1-methanol |
| CAS number | 515-69-5 |
| PubChem CID | 104770 [^3] |
| Chemical family | Monocyclic Sesquiterpenoid |
| Molecular formula | C15H26O |
| Molecular mass | 222.37 g/mol |
| Stereochemistry | Chiral; natural material is predominantly (−)-α-bisabolol (levomenol, CAS 23089-26-1). Commercial standards are usually racemic; enantiomers are kept distinct |
Aroma and sensory character
Mild, sweet, floral, warm chamomile-like scent.
Occurrence outside cannabis
- German Chamomile (Matricaria recutita)
- Candeia tree (Eremanthus erythropappus)
Physical properties
| Property | Value |
|---|---|
| Standard boiling point | 153 °C |
| Reference pressure | 0.667 kPa (5 mmHg) — reduced pressure [^1] |
| Data source | Secondary literature; NIST WebBook (CAS 515-69-5) lists no normal boiling point |
Thermal-extraction context
Note: The listed boiling point of 153 °C is measured under reduced pressure (5 mmHg / 0.667 kPa) [^1]. At standard 101.3 kPa atmospheric pressure, the boiling point is estimated to exceed 300 °C; this atmospheric estimate is a calculation from secondary literature, not a direct measurement.
Reported biological activity
Human evidence
Topical application research reports skin-soothing and anti-inflammatory activity, but the supporting data are drawn substantially from animal and cell models, with limited human trials [^2].
Animal or laboratory evidence
Rodent and cell models report analgesic, anti-inflammatory, and antimicrobial activity 1.
Traditional or anecdotal claims
Long tradition of use in soothing chamomile teas and cosmetic preparations.
Cannabis laboratory results
Measured at 0.66–0.68 mg/g dry weight in two US hemp cultivars by validated GC-MS of hydrodistilled essential oil — consistently a minor terpene (<1 mg/g) where detected 2. No peer-reviewed concentration data were located for concentrates. Check Lab Results for quantifiable levels.
Sources
Related pages
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Eddin LB, Jha NK, Goyal SN, et al. Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol. Nutrients. 2022;14(7):1370. doi:10.3390/nu14071370. PMID 35405982. ↩
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Joy N, et al. A Validated GC-MS Method for Major Terpenes Quantification in Cannabis sativa L. Essential Oil. 2025. PMC12670203; PMID 40042239. ↩
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