Geraniol

Identity

Property Value
Preferred name Geraniol
IUPAC name (2E)-3,7-dimethylocta-2,6-dien-1-ol
CAS number 106-24-1
PubChem CID 637566
Chemical family Acyclic Monoterpene Alcohol
Molecular formula C10H18O
Molecular mass 154.25 g/mol
Stereochemistry No chiral centers. The (2E) geometric isomer is geraniol; the (2Z) isomer is nerol. Do not collapse the pair [^1]

Aroma and sensory character

Sweet, rose-like, floral, and citrus-herbaceous character.

Occurrence outside cannabis

  • Rose (Rosa species)
  • Geranium (Pelargonium species)
  • Lemongrass (Cymbopogon species)
  • Citronella (Cymbopogon nardus)

Physical properties

Property Value
Standard boiling point ≈229–230 °C at 760 mmHg [^1]
Reference pressure 101.325 kPa
Data source NTP 1992 via PubChem (CID 637566); Sigma-Aldrich catalog value; consistent across NTP, Sigma-Aldrich, and ChemicalBook [^1]

Thermal-extraction context

Geraniol is a low-volatility monoterpene alcohol; in dry-herb vaporizer chambers it volatilizes by vapor-pressure-driven evaporation from the plant matrix, not by bulk boiling.

Reported biological activity

Human evidence

No controlled human study of inhaled isolated geraniol was identified in this archive’s literature review (as of 2026-08-08).

Animal or laboratory evidence

In vitro studies of cannabis terpenes report CB1-receptor negative allosteric modulation, with geraniol among the terpenes tested 1; broad-spectrum antimicrobial and anti-inflammatory activity has also been reported in vitro. Concentrations exceed plausible cannabis-inhalation exposure.

Traditional or anecdotal claims

Long use in perfumery and traditional rose-based preparations; geraniol and its autoxidation products are recognized contact sensitizers in fragrance use.

Cannabis laboratory results

Published peer-reviewed analyses place geraniol at trace or below-quantification levels: not detected or trace in Finola hemp (Booth et al. 2017) 2, and below the LOQ in two US hemp cultivars using a validated hydrodistillation/GC-MS method 3. Marketing sources claim elevated geraniol in specific cultivars, but no batch-level peer-reviewed data substantiate this. Consult Lab Results for batch-level measurements.

Sources

  1. LaVigne JE, Hecksel R, Keresztes A, Streicher JM. Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity at CB1 receptors. Sci Rep. 2021;11:8232. doi:10.1038/s41598-021-87740-8. PMID 33859287. (In vitro CB1 pharmacology; geraniol among the tested terpenes. Note: an earlier draft of this record cited a non-existent “Cannabimimetic phytochemicals in the diet” article to LaVigne; that citation was incorrect and has been replaced.) ↩

  2. Booth JK, Page JE, Bohlmann J. Terpene synthases from Cannabis sativa. PLoS One. 2017;12(3):e0173911. doi:10.1371/journal.pone.0173911. PMID 28355238. (Terpene profiles of cannabis/hemp cultivars, incl. ‘Finola’.) ↩

  3. Joy N, et al. A Validated GC-MS Method for Major Terpenes Quantification in Cannabis sativa L. Essential Oil. 2025. PMC12670203; PMID 40042239. ↩