Sabinene
Identity
| Property | Value |
|---|---|
| Preferred name | Sabinene |
| IUPAC name | 4-methylene-1-(propan-2-yl)bicyclo[3.1.0]hexane |
| CAS number | 3387-41-5 |
| PubChem CID | 18818 [^4] |
| Chemical family | Bicyclic Monoterpene |
| Molecular formula | C10H16 |
| Molecular mass | 136.23 g/mol |
| Stereochemistry | Chiral; both (+)- and (−)-enantiomers occur in nature, with the (−)-form predominant in many essential oils [^1] |
Aroma and sensory character
Spicy, woody, citrus, and pepper-like character typical of the thujene family.
Occurrence outside cannabis
- Black pepper (Piper nigrum)
- Carrot (Daucus carota)
- Nutmeg (Myristica fragrans)
- Marjoram (Origanum majorana)
- Juniper (Juniperus species)
Physical properties
| Property | Value |
|---|---|
| Standard boiling point | ≈164 °C (NIST: 436.7 K and 437 K across two determinations) [^1] |
| Reference pressure | 101.325 kPa |
| Data source | NIST Chemistry WebBook (SRD 69), CAS 3387-41-5, phase change data [^1] |
Thermal-extraction context
Sabinene is a relatively volatile bicyclic monoterpene and contributes to early headspace release from botanical matrix.
Reported biological activity
Human evidence
No verified controlled human study of inhaled isolated sabinene was identified for this archive; aromatherapy studies used whole essential oils, not the isolated compound [^2].
Animal or laboratory evidence
In vitro studies report antimicrobial, antioxidant, and antiangiogenic activity at micromolar-to-percent concentrations; an oral mouse study (10–50 mg/kg) reports reduced neuroinflammatory markers. None establish effects at cannabis-relevant inhaled exposure 1.
Traditional or anecdotal claims
Pepper and juniper preparations used traditionally for circulation and digestion.
Cannabis laboratory results
Trace-level: ≤0.005 mg/g dry weight in dried flower (chemotype I) and lower in chemotype III, per a pooled literature survey 2. Consult Lab Results for batch-level measurements.
Sources
Related pages
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No publicly reachable primary source is currently cited for the remaining details in this footnote. The details remain approximate or unverified and are not treated as verified archive facts. ↩
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Chacon FT, Raup-Konsavage WM, Vrana KE, Kellogg JJ. Secondary Terpenes in Cannabis sativa L.: Synthesis and Synergy. Biomedicines. 2022;10(12):3142. doi:10.3390/biomedicines10123142. PMID 36551898. ↩
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